Quantifying the uncertainties in theoretical models has become a focus of the nuclear physics community over the past several years. In reaction theory, there are several sectors where uncertainties are introduced, including model simplifications, the parameterization of the potentials and the use of effective interactions. Understanding each of these sources and rigorously quantifying the degree to which these impact calculated observables is crucial to move the field forward. We begin this process by quantifying the uncertainties that are introduced by fitting the parameters of the nucleon-target interaction to data. One example will be discussed, trends summarized, and the exciting path forward will be explored.